EVALUATION OF SERUM ANTIOXIDANT CAPACITY AND LIVER FUNCTIONS IN HEPATITIS B AND C VIRAL INFECTIONS
نویسندگان
چکیده
OBJECTIVE: To investigate the serum antioxidant capacity and status of liver function parameters in Hepatitis B virus (HBV) C Virus (HCV) infected patients. METHODS: In this case-control study, fifty patients with HBV (28 male & 22 females), HCV females) age gender matched healthy controls were enrolled from May to August 2016. The was determined by measuring trolox equivalent oxidant (TEAC) through Ferric Reducing Ability Plasma assay. Serum levels alkaline phosphates (ALP), Alanine amino transferase (ALT) Albumin estimated. Results: ALT (U/L) 119.69±5.03 24.3±3.01 controls; 176.34±75.48 25±3.01 female Controls; 114.71±5.03 22.61±2.33 165±5.03 Controls respectively. ALP 317.69±5.13, 240.17±23.9 controls, 159.34±5.03 138.4±3 129.28±4.57, 230.47±33.5 169±3.65 165.10±5.70 respectively (p<0.01). TEAC (μg/mL) 266.1±13.71, 413±18.21, 214.42±11.1, 395.71±16.33 control as compared 264.6±14.55, 409.8±17.54, 273.4±13.84 395.5±14.23 CONCLUSION: A significantly high induced oxidative stress deranged observed patients, suggesting a possible association between viral pathogenesis level stress.
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ژورنال
عنوان ژورنال: Khyber Medical University Journal
سال: 2022
ISSN: ['2305-2643', '2305-2651']
DOI: https://doi.org/10.35845/kmuj.2022.21955